The European Factories of the Future are expected to provide global manufacturing competitiveness, but also to create a large amount of work opportunities for the European population. Future factory workers are therefore key resources for industrial competitiveness as well as important consumers. However, as previously stated, the changing demographics and high skill requirements faced by European industry pose new challenges. Workers with high knowledge and skills (“knowledge workers”) will be scarce resources. Research efforts within Horizon 2020 must address ways to increase the number of people available for, and interested in, manufacturing tasks. This includes the following important aspects of the human resources: - New technology-based approaches to accommodate age-related limitations, through ICT and automation - New technical, educational, and organisational ways to increase the attractiveness of factory work to the young potential workforce, the existing workforce, the potential immigrant workforce, and the older workforce - New approaches to skill- and competence development, as well as skill and knowledge management, to increase competitiveness and be part of the global knowledge society - New ways to organise and compensate factory knowledge workers - New factory human-centric work-environments based on safety and comfort - Ways to integrate future factory work in global and local societal agendas and social patterns