Cloud-based simulation for non-invasive intercranial pressure measurement

The non-invasive accurate and quick measurement of the intracranial pressure (ICP) is of paramount importance for the diagnosis and treatment of neurological diseases, brain injuries and other neuro-pathologies. The world’s first accurate, non-invasive ICP measurement device, based on two-depth ultrasound Doppler technology, has been developed by a Lithuanian SME, Vittamed. The challenge facing the partners in this experiment was to create mathematical models and develop the necessary software tools to enable simulations of cerebral blood flow in the ophthalmic artery. The computational requirements of this made it necessary to adapt the software tools to run on an HPC system. The goal was to demonstrate the feasibility and benefits of such simulations via a pay-per-use Cloud-based-HPC solution. 

An internal Carotid/Opthalmic Artery model has been developed, based on MRI imaging, and used to simulate blood flow. This model has been tested and optimised to run on a multi-processor HPC system. It will be used by Vittamed in the future development of its non-invasive ICP measurement technology.